Block listing Interim Review

Name of company:

Proteome Sciences plc

Name of scheme:

2004 Share Option Plan

2011 Share Option Plan

Period of return:

1 April 2018 to 30 September 2018

Number of ordinary shares of 1 pence each in the company ("Ordinary Shares") not issued under the scheme at the end of the last period:

498,596

Number of Ordinary Shares issued under the scheme during the period:

-

Number of Ordinary Shares cancelled under the scheme during the period:

-

Balance of Ordinary Shares under scheme not yet issued at end of period:

498,596

Number and class of Ordinary Shares originally admitted under scheme and the date of admission

1,000,000 Ordinary Shares - 26^th October, 2004