Notice of Results - Update

17 April 2020

Avacta Group plc

("Avacta" or "the Group" or "the Company")

Notice of Results - Update

Avacta Group plc (AIM: AVCT), the developer of Affimer® biotherapeutics and reagents, today announces that, due to the timing of the General Meeting and completion of the proposed Admission of both the Placing Shares and Subscription Shares on 23 April 2020, it will now announce its financial results for the 17 months ended 31 December 2019 on Wednesday, 6 May 2020.

The analyst briefing due to be held on Tuesday, 21 April 2020 will now be held by Alastair Smith, Chief Executive Officer, and Tony Gardiner, Chief Financial Officer, by webcast presentation, followed by a Q&A session at 09.30 hrs on Wednesday, 6 May 2020. Pre-registration is required for attendance to the call. To confirm attendance, please email [email protected] and you will be sent the link to join.

The shareholder and investor meeting that was due to be held on Wednesday, 22 April 2020 will now take place as a webcast presentation, followed by a Q&A session, at 17.00 hrs on Wednesday, 6 May 2020. You can register and access the shareholder and investor webcast via the following link:

https://webcasting.brrmedia.co.uk/broadcast/5e985bc231da814c9fc6a477.

Alastair Smith, Chief Executive Officer, and Tony Gardiner, Chief Financial Officer, will host the call and look forward to responding to questions from existing and prospective investors.

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For further information from Avacta Group plc, please contact:

About Avacta Group plc - https://www.avacta.com

Avacta is developing novel cancer immunotherapies combining its two proprietary platforms - Affimer^® biotherapeutics and pre|CISION™ tumour targeted chemotherapy. With this approach, the Company aims to address the lack of a durable response to current immunotherapies experienced by most patients. The Company's therapeutics development activities are based in Cambridge, UK.

The Company benefits from near-term revenues generated from Affimer reagents for diagnostics, bioprocessing and research, through a separate business unit based in Wetherby, UK.

The Affimer platform is an alternative to antibodies derived from a small human protein. Despite their shortcomings, antibodies currently dominate markets worth in excess of $100bn.  Affimer technology has been designed to address many of these negative performance issues, principally: the time taken, and the reliance on an animal's immune response, to generate new antibodies; poor specificity in many cases; large size and cost. 

Avacta's pre|CISION targeted chemotherapy platform, releases active chemotherapy only in the tumour, thereby limiting systemic exposure and damage to healthy tissues, and thereby improving the overall safety and therapeutic potential of these powerful anti-cancer treatments. 

By combining these two platforms the Company is building a wholly owned pipeline of novel cancer therapies with the aim of creating effective treatments for all cancer patients including those who do not respond to existing immunotherapies. Avacta expects to take its first drug, a pre|CISION targeted form of the standard-of-care Doxorubicin, into the clinic towards the end of 2020.

Avacta has established drug development partnerships with pharma and biotech, including with Moderna Therapeutics Inc., a deal with LG Chem worth up to $310m, a partnership with ADC Therapeutics to develop Affimer drug conjugates and has established a joint venture in South Korea with Daewoong Pharmaceutical focused on cell and gene therapies incorporating Affimer immune-modulators. Avacta actively seeks to license its proprietary platforms in a range of therapeutic areas.

Avacta diagnostics business unit works with partners world-wide to develop Affimers for evaluation by those third parties with the objective of establishing royalty bearing license deals. The Company is also developing a small in-house pipeline of Affimer-based diagnostic assays for licensing.

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