NOTICE OF EARLY REDEMPTION - ISIN: XS2359958241

NOTICE OF EARLY REDEMPTION

SANTANDER UK PLC

(the "Issuer")

GBP 1,100 Preference Share-linked Autocallable Notes due 2027

ISIN: XS2359958241

(the "N&C Securities")

This notice relates to the above mentioned N&C Securities issued by the Issuer pursuant to the prospectus  relating to its Structured Note and Certificate Programme dated 19 March 2021, as supplemented from time to time (the "Base Prospectus") and the pricing supplement relating to the N&C Securities dated 2 July 2021 (the "Final Terms").

The Issuer hereby gives notice that the Issuer will redeem all outstanding N&C Securities on 20 August 2021 (the "Redemption Date") pursuant to condition 6.2 (Redemption at the Option of the Issuer (Issuer Call)) of the terms and conditions of the N&C Securities contained in the base Prospectus (the "Conditions"), having obtained the consent of the Financial Services Authority for such redemption. The Issuer will also request the cancellation of the listing of the Notes on the London Stock Exchange with effect on and from the Redemption Date.

Capitalised terms used in this notice shall have the same meanings as those ascribed to them in the Conditions.

Santander UK plc                                                                                 Dated: 16 July 2021

For further information, please contact:

Structured Notes Desk

Santander UK plc

2 Triton Square

Regent's Place

London NW1 3AN

Tel: +44 (0) 20 7756 7000

Email: [email protected]