| 21/06/22 | 07:00:06 | 21 Jun 2022 | | Eplontersen Ph III trial met co-primary endpoints | RNS |
| 06/06/22 | 07:00:09 | 6 Jun 2022 | | Enhertu efficacy results in HER2-low breast cancer | RNS |
| 01/06/22 | 15:00:00 | 1 Jun 2022 | | Block listing Interim Review | RNS |
| 01/06/22 | 15:00:00 | 1 Jun 2022 | | Total Voting Rights | RNS |
| 20/05/22 | 16:00:04 | 20 May 2022 | | Director/PDMR Shareholding | RNS |
| 09/05/22 | 13:00:01 | 9 May 2022 | | Appointment of joint corporate brokers | RNS |
| 06/05/22 | 16:00:01 | 6 May 2022 | | Director/PDMR Shareholding | RNS |
| 05/05/22 | 07:10:02 | 5 May 2022 | | Enhertu approved in US for 2L HER2+ breast cancer | RNS |
| 05/05/22 | 07:05:01 | 5 May 2022 | | Farxiga HFpEF Phase III trial met primary endpoint | RNS |
| 05/05/22 | 07:00:04 | 5 May 2022 | | Ultomiris NMOSD Ph. III trial met primary endpoint | RNS |
| 04/05/22 | 07:00:04 | 4 May 2022 | | Imfinzi combo granted Priority Review for BTC | RNS |
| 03/05/22 | 15:00:02 | 3 May 2022 | | Total Voting Rights | RNS |
| 29/04/22 | 17:30:04 | 29 Apr 2022 | | Result of AGM | RNS |
| 29/04/22 | 07:05:01 | 29 Apr 2022 | | AstraZeneca plans new R&D centre in Massachusetts | RNS |
| 29/04/22 | 07:00:03 | 29 Apr 2022 | | First quarter 2022 results | RNS |
| 28/04/22 | 07:00:12 | 28 Apr 2022 | | Ultomiris approved in the US for adults with gMG | RNS |
| 27/04/22 | 07:00:11 | 27 Apr 2022 | | Enhertu granted BTD for HER2-low breast cancer | RNS |
| 25/04/22 | 07:00:08 | 25 Apr 2022 | | Tremelimumab US Priority Review for Imfinzi combo | RNS |
| 19/04/22 | 07:00:11 | 19 Apr 2022 | | Enhertu granted Priority Review for HER2m NSCLC | RNS |
| 01/04/22 | 15:00:05 | 1 Apr 2022 | | Total Voting Rights | RNS |
| 29/03/22 | 07:00:09 | 29 Mar 2022 | | Ondexxya approved in Japan for FXai reversal | RNS |
| 28/03/22 | 07:00:09 | 28 Mar 2022 | | Evusheld approved in the EU for COVID-19 | RNS |
| 25/03/22 | 15:30:06 | 25 Mar 2022 | | Director/PDMR Shareholding | RNS |
| 24/03/22 | 18:00:06 | 24 Mar 2022 | | Evusheld Positive EU CHMP Opinion | RNS |
| 24/03/22 | 07:00:10 | 24 Mar 2022 | | Update on CALLA Phase III trial for Imfinzi | RNS |
| 23/03/22 | 11:00:02 | 23 Mar 2022 | | Notice of AGM | RNS |
| 17/03/22 | 07:00:05 | 17 Mar 2022 | | Settlement of patent litigation for Ultomiris | RNS |
| 14/03/22 | 07:05:07 | 14 Mar 2022 | | Lynparza approved in US for early breast cancer | RNS |
| 14/03/22 | 07:00:11 | 14 Mar 2022 | | Update on US review of Fasenra in nasal polyps | RNS |
| 09/03/22 | 15:30:01 | 9 Mar 2022 | | Director/PDMR Shareholding | RNS |
| 07/03/22 | 15:30:01 | 7 Mar 2022 | | Director/PDMR Shareholding | RNS |
| 01/03/22 | 15:30:01 | 1 Mar 2022 | | Director/PDMR Shareholding | RNS |
| 01/03/22 | 15:00:01 | 1 Mar 2022 | | Total Voting Rights | RNS |
| 01/03/22 | 07:00:06 | 1 Mar 2022 | | AstraZeneca and Neurimmune close deal for NI006 | RNS |
| 23/02/22 | 07:00:02 | 23 Feb 2022 | | Filing of Form 20-F with SEC | RNS |
| 22/02/22 | 11:00:00 | 22 Feb 2022 | | Chair succession planning update and Annual Report | RNS |
| 21/02/22 | 07:00:09 | 21 Feb 2022 | | Enhertu improves PFS and OS in HER2-low BC | RNS |
| 16/02/22 | 07:00:08 | 16 Feb 2022 | | Saphnelo approved in EU for SLE | RNS |
| 15/02/22 | 07:00:06 | 15 Feb 2022 | | Lynparza combo delays progression risk in prostate | RNS |
| 11/02/22 | 15:30:02 | 11 Feb 2022 | | Director/PDMR Shareholding | RNS |
| 10/02/22 | 07:00:03 | 10 Feb 2022 | | AZN: Full year and Q4 2021 results | RNS |
| 01/02/22 | 15:00:05 | 1 Feb 2022 | | Total Voting Rights | RNS |
| 19/01/22 | 07:05:08 | 19 Jan 2022 | | Imfinzi improves survival in biliary tract cancer | RNS |
| 19/01/22 | 07:00:07 | 19 Jan 2022 | | Imfinzi combo shows unprecedented survival in HCC | RNS |
| 17/01/22 | 07:00:07 | 17 Jan 2022 | | Enhertu granted Priority Review for breast cancer | RNS |
| 07/01/22 | 07:00:07 | 7 Jan 2022 | | AstraZeneca and Neurimmune sign deal for NI006 | RNS |
| 05/01/22 | 07:00:08 | 5 Jan 2022 | | Transfer of rights to Eklira, Duaklir completed | RNS |
| 04/01/22 | 15:00:07 | 4 Jan 2022 | | Total Voting Rights | RNS |
| 29/12/21 | 07:00:11 | 29 Dec 2021 | | AstraZeneca and Ionis close eplontersen deal | RNS |
| 21/12/21 | 07:00:05 | 21 Dec 2021 | | Ultomiris accepted for FDA Priority Review for gMG | RNS |