Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing medicines for immune-mediated diseases, with a focus on SP001, a third-generation anti-CD40L antibody for IgG4-related disease. The company prioritizes programs that align with compelling biology, patient need, and differentiation from existing treatments. SP001 aims to inhibit a key immune signaling pathway to reduce disease activity while preserving immune cell function. Spero is also evaluating SP001's potential in other immune-mediated conditions.
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