Prospectus Supplement and Supplementary Registration Document

The following Prospectus Supplement and Supplementary Registration Document have been approved by the Financial Conduct Authority and are available for viewing:

Supplementary Prospectus dated 26 September 2022 to the NatWest Markets Plc £15,000,000,000 Euro Medium-Term Note Programme of 7 December 2021 and $10,000,000,000 144A MTN Programme dated 16 March 2022, and Supplementary Registration Document dated 26 September 2022 to the Registration Document of 16 March 2022.

To view the full document, please paste the following URL into the address bar of your browser:

http://www.rns-pdf.londonstockexchange.com/rns/7047A_1-2022-9-26.pdf

http://www.rns-pdf.londonstockexchange.com/rns/7047A_2-2022-9-26.pdf

A copy of the above Supplementary Prospectus has been submitted to the National Storage Mechanism and will shortly be available for inspection at:

https://data.fca.org.uk/#/nsm/nationalstoragemechanism    

For further information, please contact:

Mark Anwender

NatWest Treasury DCM, Head of Documentation and Funding

Tel: +44 (0) 7385 366 760

DISCLAIMER - INTENDED ADDRESSEES

Please note that the information contained in the Supplementary Prospectus and Supplementary Registration Document (and the Base Prospectus and Registration Document to which they relate) may be addressed to and/or targeted at persons who are residents of particular countries (specified in the Base Prospectus) only and is not intended for use and should not be relied upon by any person outside of these countries and/or to whom the offer contained in the Base Prospectus and the Supplementary Prospectus is not addressed. Prior to relying on the information contained in the Base Prospectus, Registration Document and the Supplementary Prospectus and Supplementary Registration Document you must ascertain from the Base Prospectus whether or not you are part of the intended addressees of the information contained therein.

Your right to access this service is conditional upon complying with the above requirement.

Legal Entity Identifier:

NatWest Markets Plc - RR3QWICWWIPCS8A4S074