GlaxoSmithKline plc

The following amendment has been made to the Publication of full year 2021 results announcement released on 7 February 2022 at 10:00am under RNS No 8776A.

The announcement date will be Wednesday 9 February 2022.

All other details remain unchanged.

The full amended text is shown below.

Publication of full year 2021 results

GlaxoSmithKline plc will announce its full year and fourth quarter 2021 results to the London Stock Exchange at 07:00 GMT on Wednesday 9 February 2022.

Analysts and investors are invited to participate in a conference call and webcast, including a presentation of the results and a Q&A session. This event will take place on the same day at 14:00 GMT.

To participate, please join the live audio webcast, which can be accessed directly via the website. The presentation will also be available on the website about one hour before the event's start.

V A Whyte

Company Secretary

7 February 2022