INTERNATIONAL BIOTECHNOLOGY TRUST PLC

(the "Company")

Information disclosed in accordance with Market Abuse Regulation ('MAR') Article 19, paragraph 11

The Company announces that it is satisfied that all inside information which the Directors and the Company may have in the period leading up to the announcement of its results for the six months ended 29 February 2024 has previously been, and will continue to be, notified via a regulatory information service (RIS). Therefore, the Company is not prohibited from dealing in its own securities.

The mandatory closed period under MAR will last until the results in respect of the half year ended 29 February 2024 are published, expected to be on or around 8 May 2024.

The Company has provided Deutsche Numis, its corporate broker, with a non-discretionary dealing instruction under which it may undertake share buybacks if, in the period leading up to the announcement of the half year results, the Directors of the Company come into the possession of any inside information.

Enquiries:

Schroder Investment Management Limited

Kerry Higgins

Tel: 0207 6586189