3 April 2024

IXICO plc

("IXICO" or the "Company")

Imeka Collaboration Agreement

IXICO plc (AIM: IXI), the medical imaging advanced analytics company delivering intelligent insights in neuroscience, announces a collaboration agreement with IMEKA Solutions Inc. ("Imeka") to provide access to Imeka's suite of services for white matter¹ imaging deployed in Alzheimer's Disease (AD) and Multiple Sclerosis (MS) clinical trials, amongst other CNS indications.

Imeka's diffusion MRI algorithms will be made available to IXICO's global biopharma clients, streamlining access to these tools through a combined study delivery.  With a single contracting line, this simplifies the procurement process whilst improving access to a broader suite of white matter imaging AI tools and solutions delivered by IXICO.  White matter imaging is of increasing interest for neuroinflammation, axonal integrity and myelin integrity, in particular in AD and MS clinical trials amongst other CNS indications.

Giulio Cerroni, Chief Executive Officer of IXICO, commented:

''We are pleased to be partnering with Imeka to further the understanding of debilitating neurological diseases through the power of advanced imaging technology, in the hope that our partnership will bring clarity and accessibility to previously untapped possibilities of image analysis."

Jean-René Bélanger, Chief Executive Officer of Imeka, commented:

"We are delighted to contribute to IXICO's outstanding imaging CRO services. Our collaboration reflects a shared commitment to integrating advanced imaging technologies into treatment development. By offering Imeka's expertise into IXICO's, we anticipate the emergence of new opportunities that will ultimately enhance patient care and provide significant benefits to patients and their families."

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¹ White matter are areas of the brain that primarily consists of myelinated axons. In the brain, white matter is found closer to the centre of the brain, whereas the outer cortex is mainly grey matter

This is an RNS Reach announcement and the information contained is not considered to have a significant impact on management's expectations of the Group's performance. RNS Reach is an investor communication service aimed at assisting listed and unlisted (including AIM quoted) companies to distribute non-regulatory news releases into the public domain. Information required to be notified under the AIM Rules for Companies, Market Abuse Regulation or other regulation would be disseminated as an RNS regulatory announcement and not on RNS Reach.

About IXICO | Advanced Analytics | Intelligent Insights.

IXICO is dedicated to delivering insights in neuroscience to help transform the advancement of investigational therapies for neurological diseases, such as Huntington's disease, Parkinson's disease and Alzheimer's disease. The Company's purpose is to advance medicine and human health by turning data into clinically meaningful information, providing valuable new insights in neuroscience by supporting pharmaceutical companies across all phases of CNS clinical research. IXICO's goal is to be a leading advocate of artificial intelligence in medical image analysis. 

IXICO has developed and deployed breakthrough data analytics, at scale, through its remote access technology platform, to improve the return on investment in drug development and reduce risk and uncertainty in clinical trials for the Company's pharmaceutical clients.

More information is available on www.IXICO.com

About Imeka

Imeka is the global leader in white matter microstructure imaging, combining advanced MRI processing capabilities and artificial intelligence to bring novel insights to the research and clinical communities. The company has been working with all major pharmaceutical companies developing treatments for neurodegenerative diseases and is now offering its state-of-the-art technology to physicians to directly impact patients.

More information is available on  www.imeka.ca