THIS ANNOUNCEMENT, INCLUDING THE INFORMATION CONTAINED IN IT, IS RESTRICTED AND IS NOT FOR PUBLICATION, RELEASE OR DISTRIBUTION, DIRECTLY OR INDIRECTLY, IN WHOLE OR IN PART, IN OR INTO OR FROM THE UNITED STATES, AUSTRALIA, CANADA, JAPAN, OR THE REPUBLIC OF SOUTH AFRICA OR ANY OTHER JURISDICTION IN WHICH SUCH PUBLICATION, RELEASE OR DISTRIBUTION WOULD BE UNLAWFUL.

22 December 2022

Kistos Holdings plc

Scheme of arrangement legally effective and Admission of Ordinary Shares to trading

The board of directors ("Board") of Kistos Holdings plc ("Kistos" or "Company" or, together with its subsidiary or subsidiary undertakings, the "Group") (AIM: KIST) is pleased to announce that the order of the High Court of Justice of England and Wales (the "Court") sanctioning the scheme of arrangement ("Scheme") under Part 26A of the Companies Act 2006 has been delivered to the Registrar of Companies, and as such, the Scheme is now effective and Kistos is now the holding company of the Group.

The Board is also pleased to announce the admission of Kistos's ordinary shares of nominal value 10 pence each ("Ordinary Shares") to trading on the AIM market of the London Stock Exchange ("Admission") at 8.00 a.m. today. On Admission, the Company will have a total of 82,863,743 Ordinary Shares in issue.

Timeline*:

All references to time in this announcement are to London, England time, unless otherwise stated.

*The Company will advise any changes to times and dates by RNS.

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