1 June 2022

Microsaic Systems plc

("Microsaic" or the "Company")

Posting of Annual Report, Notice of Annual General Meeting

and

Investor Presentation

Microsaic Systems plc (AIM: MSYS), the developer of point of need mass spectrometry ("MS") instruments and related services, announces that its 2021 Annual Report and Notice of Annual General Meeting ("Notice of AGM"), are available on the Company's website at https://www.microsaic.com/investors/documents/. These documents will be posted to shareholders today, together with the Form of Proxy for voting at the Annual General Meeting ("AGM").

The Company will hold its AGM at the offices of Turner Pope Investments (TPI) Limited (the Company's joint broker) at 8 Frederick's Place, London, EC2R 8AB on 30 June 2022 at 10.00am.

Arrangements for the AGM

The Board is keen to ensure that the health and safety of shareholders, directors, employees and other key stakeholders remains a priority and as such, all shareholders are urged to appoint the Chairman of the AGM as their proxy, with voting instructions.

Shareholders are requested to notify the Company Secretary, via [email protected] in advance, if they wish to attend the AGM in person, and should note that in the interests of safety they may be refused entry if, in the opinion of the Company, the numbers in attendance becomes unsafe. The Board will continue to monitor COVID-19 developments as well as any further UK Government advice and will issue a further statement if the above arrangements require any amendment.

Investor Presentation

The Company's Executive Chairman, Gerry Brandon, will provide a live presentation at 10.00am on 30 June 2022, via the Investor Meet Company platform, relating to the Annual Results for the year ended 31 December 2021.

The presentation is open to all existing and potential shareholders. Questions can be submitted pre-event via the Investor Meet Company dashboard up until 9.00am the day before the meeting or at any time during the live presentation.

Investors can sign up to Investor Meet Company for free and add Microsaic Systems plc via https://www.investormeetcompany.com/microsaic-systems-plc/register-investor. Investors who already follow Microsaic Systems plc on the Investor Meet Company platform will automatically be invited.

About Microsaic

Microsaic floated on AIM in 2011 to develop and commercialise micro-engineering chip-based mass spectrometry equipment. Having invested c. £30m over 20 years of development, Microsaic has a robust and innovative patent portfolio in cutting-edge technology designed and developed for "Industry 4.0" application. Microsaic serves markets in Human Health, Environmental Health and Diversified Industries. Microsaic's system solutions enable analytical detection and characterisation at the point-of-need, whether within a conventional laboratory setting, or within a bioprocessing facility for continuous MS detection data at multiple steps in the process workflow.

Microsaic's products and systems are commercially available through global markets via a network of regional and local partners, targeting its core laboratory, manufacturing and point of need applications.