ONDINE BIOMEDICAL INC.

("Ondine Biomedical", "Ondine" or the "Company")

Ondine food-safe photodisinfection update

Canadian life sciences company, Ondine Biomedical, has concluded the first development phase of a new food-safe photodisinfection technology for Canada's meat packing industry. The findings which will be presented at a webinar on Wednesday 12 April, 2023 will report on identifying and screening potential food-safe photosensitizers for efficacy against bacterial biofilms common in food processing.

In December 2022 Ondine was awarded nearly $735,000 to undertake this research, which was funded in part by the Government of Canada under the Canadian Agricultural Partnership's AgriScience Program, a federal, provincial, territorial initiative. The AgriScience Program aims to accelerate the pace of innovation by providing funding and support for pre-commercial science activities and cutting-edge research that benefits consumers and the agriculture and agri-food sector.

The food-processing industry has a need for the development of technologies to reduce the incidence of food-borne pathogens including bacteria, fungi, viruses, and protozoa. Eradicating these invasive microbes will help protect the $9.4 billion (2021) Canadian meat export industry, as well enhance the lives and welfare of consumers by reducing the incidence of food-borne illnesses.

Ondine is the world leader in the development of photodisinfection technology, and has already proven the safety and effectiveness of the technology at hospitals across Canada where it is used to decolonize the nose prior to surgery to prevent surgical site infections ( SSIs) - Vancouver General Hospital has reported reducing SSIs in patients undergoing major surgery by over 50%.

Webinar:           "Photodisinfection for Food Safety"

Timing:               Wednesday 12 April, 2023 at 12:00pm EST / 5:00pm BST

Registration:      https://go.marketing.ondinebio.com/WebRegistration

Panelists:

·    Dr. Richard Rusk (DVM, MD, CCFP, MPH, DipZBPV, FRSPH), Prevention Medicine Specialist and former Manitoba Medical Officer of Health

·    Dr. Nicolas Loebel, Ondine Biomedical President and Chief Technology Officer

·    Dr. Joseph Ross, Senior Scientist at Chinook Contract Research

**ENDS**

Microbial foodborne disease

Foodborne illnesses are a major public health concern due to the high risk of microbial contamination of food. In 2010, more than 580 million illnesses and 351,000 deaths worldwide were associated with food contaminated by enteric pathogens according to a World Health Organization (WHO) estimate. Meat and meat-based products are particularly prone to contamination, accounting for more than 16% of total foodborne outbreaks in Europe in 2016.

Source:  Int. J. Environ. Res. Public Health 2020, 17, 688; doi:10.3390/ijerph17030688

About photodisinfection

Ondine's photodisinfection is a patented technology using a proprietary photosensitizer (non-antibiotic, light-activated solution) to destroy pathogens. When illuminated with a specific wavelength of light, the photosensitizer is activated, causing an oxidative burst that is lethal to all types of pathogens.

Ondine's nasal photodisinfection system has a CE mark and is approved in Canada and several other countries under the name Steriwave™. It has been used in Canada for over ten years, with no serious adverse events reported. In the US, it is currently undergoing clinical trials for regulatory approval.

About Ondine Biomedical Inc.

Ondine Biomedical Inc. is a Canadian headquartered company innovating in the field of photodisinfection therapies. Ondine has a pipeline of investigational products, based on its proprietary photodisinfection platform, in various stages of development. Products beyond nasal photodisinfection include therapies for a variety of medical indications such as chronic sinusitis, ventilator-associated pneumonia, burns, and other indications.