The following amendments have been made to the 'Net Asset Value ' announcement released on 19/08/2022 at 12:06 under RNS No 6468W

The incorrect dates have been updated from the previous announcement

All other details remain unchanged.

The full amended text is shown below.

POLAR CAPITAL GLOBAL HEALTHCARE TRUST PLC ("the Company")

Legal Entity Identifier: 549300YV7J2TWLE7PV84

19^th August 2022

Net Asset Values

As at close of business on 18^th August 2022 the Company's unaudited Net Asset Value, calculated in accordance with the guidelines of the Association of Investment Companies, was:

Ordinary Share (cum income)                                                                   345.54p

PCGH ZDP PLC

Legal Entity Identifier: 5493004C3YRF9HEVQI09

As at close of business on 18^th August 2022 the redemption value of the ZDP Shares was:

Zero Dividend Preference (ZDP) Share                                                  116.50p

The Redemption Value of the ZDP Shares compounds annually at 3% and accrues daily, with a redemption value of 122.99p per ZDP Share on 19 June 2024.

For further information, please call:

Oluwafemi Adesuyi

Investment Trust Operations Department

Polar Capital Partners Limited

Tel: 020 7227 2700