Poolbeg Pharma plc

Appointment of Dr Adrian Kilcoyne to Scientific Advisory Board

12 March 2026- Poolbeg Pharma (AIM: POLB, 'Poolbeg' or the 'Company'), a clinical-stage biopharmaceutical company with a core focus on transforming the cancer immunotherapy field, announces the appointment of Dr Adrian Kilcoyne to its Scientific Advisory Board.

Dr Kilcoyne brings over 20 years of clinical expertise with strategic drug development leadership, focusing on innovative therapies that address unmet medical needs in oncology and immunology and, in particular, brings deep knowledge of haematological malignancies, T-cell therapies and Cytokine Release Syndrome ("CRS").

Dr Kilcoyne is currently Chief Medical Officer at Cellectis SA focusing on the development of allogeneic CAR-T therapies. He was previously Chief Medical Officer and Head of Research & Development at Celularity Inc., where he advanced oncology-focused allogeneic CAR-T and natural killer (NK) cell therapy programmes. He also served as Chief Medical Officer at Humanigen Inc., helping to build the immunology and oncology portfolios, focusing on the cytokine pathway, CAR-T therapies, immunotherapies and Antibody Drug Conjugates in haematology and solid tumours. Across his career, he has held senior leadership roles in research & development, medical affairs, commercial strategy, health economics and outcomes research at major pharmaceutical and biotechnology companies including AstraZeneca, Celgene, Sanofi, Roche, and Eli Lilly.

Dr Kilcoyne's clinical training began after graduating from Trinity College Dublin Medical School. He trained in Gynaecological Oncology at Hammersmith Hospital, London and later pursued advanced public health training at Oxford, earning a Master's in Public Health. He subsequently completed professional training in pharmaceutical medicine and earned an MBA from Warwick Business School.

Prof Luke O'Neill, Chair of the Scientific Advisory Board of Poolbeg Pharma, said: "We are delighted to welcome Dr Kilcoyne to Poolbeg's Scientific Advisory Board. He brings a wealth of experience in oncology and cell therapy drug development, combined with deep clinical insight and regulatory expertise which will be invaluable to us as we progress POLB 001 through the TOPICAL trial with the ultimate aim of transforming cancer care for patients and healthcare systems."

Dr Adrian Kilcoyne, Scientific Advisory Board Member of Poolbeg Pharma, said: "I am pleased to join the Scientific Advisory Board of Poolbeg Pharma and to have the opportunity to contribute to the development of POLB 001. Having seen first-hand both the clinical impact on patients and the economic burden on healthcare systems posed by immunotherapy related CRS, I believe POLB 001 has the potential to transform the patient experience. The prevention of CRS remains a significant unmet need and addressing it may enable access for a greater number of patients to life-saving immunotherapies."    

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About Poolbeg Pharma plc 

Poolbeg Pharma plc (AIM: POLB) is a clinical-stage biopharmaceutical company with a core focus on transforming the cancer immunotherapy field. The Company's lead asset, POLB 001, has the potential to expand administration of cancer immunotherapies from centralised specialist cancer centres into community hospitals by making the treatments safer through the prevention of the life-threatening side effect, Cytokine Release Syndrome (CRS). As such, POLB 001 could increase the number of patients that can receive these life-saving treatments, thereby increasing the market opportunity. Poolbeg is also advancing the development of a patient-friendly therapy for obesity with an oral encapsulated GLP-1, offering a differentiated approach within one of the world's largest markets. With multiple near-term clinical value inflection points, and an experienced team with a proven track record, Poolbeg is focussed on partnering its high value programmes that are targeting large markets and addressing critical unmet medical needs. 

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