17 July 2026

ValiRx PLC

("ValiRx" or the "Company")

Result of AGM & Issue of Warrants

Director and PDMR Shareholding

Directorate Change

London, UK - ValiRx Plc (AIM: VAL), a life science company focusing on early-stage cancer therapeutics and women's health announces that at its Annual General Meeting ("AGM") held earlier today, all resolutions were duly passed.

Details of the votes received will be available on the Company's website shortly.

Issue of Warrants

Pursuant to the Fundraising and in connection with the issuance of the Fee Shares the Company has issued 577,500,000 Fundraising Warrants. The Fundraising Warrants will be exercisable at a price of 0.28 pence per Ordinary Share and are exercisable at any time until the third anniversary of date of grant.

In addition, the Company has issued 53,750,000 Broker Warrants. The Broker Warrants will be exercisable at the Issue Price. The Broker Warrants are exercisable at any time until the third anniversary of date of grant.

Terms used but not defined in this announcement have the same meaning as set out in the Company's announcement released at 7.00 a.m. on 15 May 2026.

Directorate Change

The Company announces that Cathy Tralau-Stewart did not stand for re-election as a Non-Executive Director at the Company's AGM held earlier today. Accordingly, following the conclusion of the AGM, Cathy has stepped down from the Board with immediate effect.

The Board would like to thank Cathy for her valuable contribution to the Company during her tenure and wishes her every success in the future.

Cathy Tralau-Stewart commented:

"I am committed to supporting the broader translation of academic science to patients and as such I think my time is best spent focusing on my leadership of the Milner Therapeutics Institute, University of Cambridge.

I am confident in the current management and scientific teams and that focusing the portfolio on later stage pre-clinical projects is important for the Company to deliver for shareholders.

I wish ValiRx and the team the best for the future."

Martin Gouldstone, Non-Executive Chairman of ValiRx commented:

"On behalf of the Board of VAL plc I would like to say a big thank you to Cathy for her scientific leadership in both her roles as CSO and more recently on the Board. Cathy leaves VAL in a much stronger position scientifically. We wish her well as she concentrates on her executive role at the Milner Therapeutics Institute."

The Directors of the Company take responsibility for this announcement.

*** ENDS ***

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Notes for Editors

About ValiRx

ValiRx is a life science company focused on early-stage cancer therapeutics and women's health, accelerating the translation of innovative science into impactful medicines to improve patient lives.

ValiRx provides the scientific, financial, and commercial framework for enabling rapid translation of innovative science into clinical development.

Using its extensive and proven experience in research and drug development, the team at ValiRx selects and incubates promising novel drug candidates and guides them through an optimised process of development, from pre-clinical studies to clinic and investor-ready assets.

ValiRx connects diverse disciplines across scientific, technical, and commercial domains, with the aim of achieving a more streamlined, less costly, drug development process. The team works closely with carefully selected collaborators and leverages the combined expertise required for science to advance.

Lead candidates from ValiRx's portfolio are outlicensed or partnered with investors through ValiRx subsidiary companies for further clinical development and commercialisation.

ValiRx listed on the AIM Market of the London Stock Exchange in October 2006 and trades under the ticker symbol: VAL.

For further information, visit: www.valirx.com