The following base prospectus supplement has been approved by the UK Financial Conduct Authority and is available for viewing:

Second supplement (the "Second Supplement") to the base prospectus dated 18 July 2025, as supplemented by the first supplement dated 17 September 2025 (the "Base Prospectus") relating to the £1,000,000,000 UK Debt Issuance Programme of NATIXIS and Natixis Structured Issuance S.A..

To view the full document, please paste the following URL into the address of your browser.

http://www.rns-pdf.londonstockexchange.com/rns/9811I_1-2025-11-25.pdf

For further information, please contact:

Name:  Régis PARRIMOND

Email:   [email protected]

Tel:        +33 1 58 55 99 54

Name:  Hester BERENSCHOT

Email:   [email protected]

Tel:        +44 (0)20 3216 9288

DISCLAIMER - INTENDED ADDRESSEES

Please note that the information contained in the Base Prospectus and the Second Supplement may be addressed to and/or targeted at persons who are residents of particular countries (specified in the Base Prospectus) only and is not intended for use and should not be relied upon by any person outside these countries and/or to whom the offer contained in the Base Prospectus is not addressed. Prior to relying on the information contained in the Base Prospectus and the Second Supplement you must ascertain from the Base Prospectus whether or not you are part of the intended addressees of the information contained therein. By accessing this document, you will be deemed to certify that you are located outside the United States and are not accessing the Base Prospectus from a location inside the United States.

Your right to access this service is conditional upon complying with the above requirement.