Julie TankardPurchase

15/10/2025369 shares£3,955.68

Nicola ShepherdPurchase

11/06/2025500 shares£3,854.66

Roger YatesPurchase

04/06/202510,000 shares£7,473,600.00

Nicola ShepherdPurchase

13/01/20251,000 shares£845,700.00

Hamish BailliePurchase

19/12/20241,200 shares£10,272.00

Julie TankardPurchase

04/12/20241,022 shares£993,833.68

Hamish BailliePurchase

27/11/20243,000 shares£27,930.00

Roger YatesPurchase

14/03/20245,000 shares£48,450.00

Hamish BailliePurchase

12/03/20243,000 shares£29,250.00

Nicola ShepherdPurchase

28/02/20241,000 shares£10,010.00

Nicola ShepherdPurchase

11/08/20231,000 shares£7,800.00

Roger YatesPurchase

14/06/202210,000 shares£7,776,400.00

Date	Director/PDMR	Type	Shares	Price	Value
15/10/2025	Julie Tankard	Purchase	369	1,072.00	£3,955.68
11/06/2025	Nicola Shepherd	Purchase	500	770.93	£3,854.66
04/06/2025	Roger Yates	Purchase	10,000	74,736.00	£7,473,600.00
13/01/2025	Nicola Shepherd	Purchase	1,000	84,570.00	£845,700.00
19/12/2024	Hamish Baillie	Purchase	1,200	856.00	£10,272.00
04/12/2024	Julie Tankard	Purchase	1,022	97,244.00	£993,833.68
27/11/2024	Hamish Baillie	Purchase	3,000	931.00	£27,930.00
14/03/2024	Roger Yates	Purchase	5,000	969.00	£48,450.00
12/03/2024	Hamish Baillie	Purchase	3,000	975.00	£29,250.00
28/02/2024	Nicola Shepherd	Purchase	1,000	1,001.00	£10,010.00
11/08/2023	Nicola Shepherd	Purchase	1,000	780.00	£7,800.00
14/06/2022	Roger Yates	Purchase	10,000	77,764.00	£7,776,400.00

Open positions only

City of Bradford - West Yorkshire Pension Fund

07/05/20251,070,689 shares4.02%

Border to Coast Pensions Partnership Ltd

09/12/20241,284,902 shares4.11%

Brewin Dolphin Limited

14/03/20231,779,234 shares4.55%

Border to Coast Pensions Partnership Ltd

15/02/20231,985,000 shares5.01%

Brewin Dolphin Limited

14/04/20222,050,951 shares5.01%

Rathbone Investment Management Ltd

03/02/20222,061,139 shares5.01%

Border to Coast Pensions Partnership Limited

17/06/20212,081,000 shares5.01%

Date	Shareholder	Shares Held	Percentage
07/05/2025	City of Bradford - West Yorkshire Pension Fund	1,070,689	4.02%
09/12/2024	Border to Coast Pensions Partnership Ltd	1,284,902	4.11%
14/03/2023	Brewin Dolphin Limited	1,779,234	4.55%
15/02/2023	Border to Coast Pensions Partnership Ltd	1,985,000	5.01%
14/04/2022	Brewin Dolphin Limited	2,050,951	5.01%
03/02/2022	Rathbone Investment Management Ltd	2,061,139	5.01%
17/06/2021	Border to Coast Pensions Partnership Limited	2,081,000	5.01%

Julie TankardPurchase

15/10/2025369 shares£3,955.68

Nicola ShepherdPurchase

11/06/2025500 shares£3,854.66

Roger YatesPurchase

04/06/202510,000 shares£7,473,600.00

Nicola ShepherdPurchase

13/01/20251,000 shares£845,700.00

Hamish BailliePurchase

19/12/20241,200 shares£10,272.00

Julie TankardPurchase

04/12/20241,022 shares£993,833.68

Hamish BailliePurchase

27/11/20243,000 shares£27,930.00

Roger YatesPurchase

14/03/20245,000 shares£48,450.00

Hamish BailliePurchase

12/03/20243,000 shares£29,250.00

Nicola ShepherdPurchase

28/02/20241,000 shares£10,010.00

Nicola ShepherdPurchase

11/08/20231,000 shares£7,800.00

Roger YatesPurchase

14/06/202210,000 shares£7,776,400.00

Date	Director/PDMR	Type	Shares	Price	Value
15/10/2025	Julie Tankard	Purchase	369	1,072.00	£3,955.68
11/06/2025	Nicola Shepherd	Purchase	500	770.93	£3,854.66
04/06/2025	Roger Yates	Purchase	10,000	74,736.00	£7,473,600.00
13/01/2025	Nicola Shepherd	Purchase	1,000	84,570.00	£845,700.00
19/12/2024	Hamish Baillie	Purchase	1,200	856.00	£10,272.00
04/12/2024	Julie Tankard	Purchase	1,022	97,244.00	£993,833.68
27/11/2024	Hamish Baillie	Purchase	3,000	931.00	£27,930.00
14/03/2024	Roger Yates	Purchase	5,000	969.00	£48,450.00
12/03/2024	Hamish Baillie	Purchase	3,000	975.00	£29,250.00
28/02/2024	Nicola Shepherd	Purchase	1,000	1,001.00	£10,010.00
11/08/2023	Nicola Shepherd	Purchase	1,000	780.00	£7,800.00
14/06/2022	Roger Yates	Purchase	10,000	77,764.00	£7,776,400.00

Open positions only

City of Bradford - West Yorkshire Pension Fund

07/05/20251,070,689 shares4.02%

Border to Coast Pensions Partnership Ltd

09/12/20241,284,902 shares4.11%

Brewin Dolphin Limited

14/03/20231,779,234 shares4.55%

Border to Coast Pensions Partnership Ltd

15/02/20231,985,000 shares5.01%

Brewin Dolphin Limited

14/04/20222,050,951 shares5.01%

Rathbone Investment Management Ltd

03/02/20222,061,139 shares5.01%

Border to Coast Pensions Partnership Limited

17/06/20212,081,000 shares5.01%

Date	Shareholder	Shares Held	Percentage
07/05/2025	City of Bradford - West Yorkshire Pension Fund	1,070,689	4.02%
09/12/2024	Border to Coast Pensions Partnership Ltd	1,284,902	4.11%
14/03/2023	Brewin Dolphin Limited	1,779,234	4.55%
15/02/2023	Border to Coast Pensions Partnership Ltd	1,985,000	5.01%
14/04/2022	Brewin Dolphin Limited	2,050,951	5.01%
03/02/2022	Rathbone Investment Management Ltd	2,061,139	5.01%
17/06/2021	Border to Coast Pensions Partnership Limited	2,081,000	5.01%

Julie TankardPurchase

15/10/2025369 shares£3,955.68

Nicola ShepherdPurchase

11/06/2025500 shares£3,854.66

Roger YatesPurchase

04/06/202510,000 shares£7,473,600.00

Nicola ShepherdPurchase

13/01/20251,000 shares£845,700.00

Hamish BailliePurchase

19/12/20241,200 shares£10,272.00

Julie TankardPurchase

04/12/20241,022 shares£993,833.68

Hamish BailliePurchase

27/11/20243,000 shares£27,930.00

Roger YatesPurchase

14/03/20245,000 shares£48,450.00

Hamish BailliePurchase

12/03/20243,000 shares£29,250.00

Nicola ShepherdPurchase

28/02/20241,000 shares£10,010.00

Nicola ShepherdPurchase

11/08/20231,000 shares£7,800.00

Roger YatesPurchase

14/06/202210,000 shares£7,776,400.00

Date	Director/PDMR	Type	Shares	Price	Value
15/10/2025	Julie Tankard	Purchase	369	1,072.00	£3,955.68
11/06/2025	Nicola Shepherd	Purchase	500	770.93	£3,854.66
04/06/2025	Roger Yates	Purchase	10,000	74,736.00	£7,473,600.00
13/01/2025	Nicola Shepherd	Purchase	1,000	84,570.00	£845,700.00
19/12/2024	Hamish Baillie	Purchase	1,200	856.00	£10,272.00
04/12/2024	Julie Tankard	Purchase	1,022	97,244.00	£993,833.68
27/11/2024	Hamish Baillie	Purchase	3,000	931.00	£27,930.00
14/03/2024	Roger Yates	Purchase	5,000	969.00	£48,450.00
12/03/2024	Hamish Baillie	Purchase	3,000	975.00	£29,250.00
28/02/2024	Nicola Shepherd	Purchase	1,000	1,001.00	£10,010.00
11/08/2023	Nicola Shepherd	Purchase	1,000	780.00	£7,800.00
14/06/2022	Roger Yates	Purchase	10,000	77,764.00	£7,776,400.00

Open positions only

City of Bradford - West Yorkshire Pension Fund

07/05/20251,070,689 shares4.02%

Border to Coast Pensions Partnership Ltd

09/12/20241,284,902 shares4.11%

Brewin Dolphin Limited

14/03/20231,779,234 shares4.55%

Border to Coast Pensions Partnership Ltd

15/02/20231,985,000 shares5.01%

Brewin Dolphin Limited

14/04/20222,050,951 shares5.01%

Rathbone Investment Management Ltd

03/02/20222,061,139 shares5.01%

Border to Coast Pensions Partnership Limited

17/06/20212,081,000 shares5.01%

Date	Shareholder	Shares Held	Percentage
07/05/2025	City of Bradford - West Yorkshire Pension Fund	1,070,689	4.02%
09/12/2024	Border to Coast Pensions Partnership Ltd	1,284,902	4.11%
14/03/2023	Brewin Dolphin Limited	1,779,234	4.55%
15/02/2023	Border to Coast Pensions Partnership Ltd	1,985,000	5.01%
14/04/2022	Brewin Dolphin Limited	2,050,951	5.01%
03/02/2022	Rathbone Investment Management Ltd	2,061,139	5.01%
17/06/2021	Border to Coast Pensions Partnership Limited	2,081,000	5.01%

Julie TankardPurchase

15/10/2025369 shares£3,955.68

Nicola ShepherdPurchase

11/06/2025500 shares£3,854.66

Roger YatesPurchase

04/06/202510,000 shares£7,473,600.00

Nicola ShepherdPurchase

13/01/20251,000 shares£845,700.00

Hamish BailliePurchase

19/12/20241,200 shares£10,272.00

Julie TankardPurchase

04/12/20241,022 shares£993,833.68

Hamish BailliePurchase

27/11/20243,000 shares£27,930.00

Roger YatesPurchase

14/03/20245,000 shares£48,450.00

Hamish BailliePurchase

12/03/20243,000 shares£29,250.00

Nicola ShepherdPurchase

28/02/20241,000 shares£10,010.00

Nicola ShepherdPurchase

11/08/20231,000 shares£7,800.00

Roger YatesPurchase

14/06/202210,000 shares£7,776,400.00

Date	Director/PDMR	Type	Shares	Price	Value
15/10/2025	Julie Tankard	Purchase	369	1,072.00	£3,955.68
11/06/2025	Nicola Shepherd	Purchase	500	770.93	£3,854.66
04/06/2025	Roger Yates	Purchase	10,000	74,736.00	£7,473,600.00
13/01/2025	Nicola Shepherd	Purchase	1,000	84,570.00	£845,700.00
19/12/2024	Hamish Baillie	Purchase	1,200	856.00	£10,272.00
04/12/2024	Julie Tankard	Purchase	1,022	97,244.00	£993,833.68
27/11/2024	Hamish Baillie	Purchase	3,000	931.00	£27,930.00
14/03/2024	Roger Yates	Purchase	5,000	969.00	£48,450.00
12/03/2024	Hamish Baillie	Purchase	3,000	975.00	£29,250.00
28/02/2024	Nicola Shepherd	Purchase	1,000	1,001.00	£10,010.00
11/08/2023	Nicola Shepherd	Purchase	1,000	780.00	£7,800.00
14/06/2022	Roger Yates	Purchase	10,000	77,764.00	£7,776,400.00

Open positions only

City of Bradford - West Yorkshire Pension Fund

07/05/20251,070,689 shares4.02%

Border to Coast Pensions Partnership Ltd

09/12/20241,284,902 shares4.11%

Brewin Dolphin Limited

14/03/20231,779,234 shares4.55%

Border to Coast Pensions Partnership Ltd

15/02/20231,985,000 shares5.01%

Brewin Dolphin Limited

14/04/20222,050,951 shares5.01%

Rathbone Investment Management Ltd

03/02/20222,061,139 shares5.01%

Border to Coast Pensions Partnership Limited

17/06/20212,081,000 shares5.01%

Date	Shareholder	Shares Held	Percentage
07/05/2025	City of Bradford - West Yorkshire Pension Fund	1,070,689	4.02%
09/12/2024	Border to Coast Pensions Partnership Ltd	1,284,902	4.11%
14/03/2023	Brewin Dolphin Limited	1,779,234	4.55%
15/02/2023	Border to Coast Pensions Partnership Ltd	1,985,000	5.01%
14/04/2022	Brewin Dolphin Limited	2,050,951	5.01%
03/02/2022	Rathbone Investment Management Ltd	2,061,139	5.01%
17/06/2021	Border to Coast Pensions Partnership Limited	2,081,000	5.01%

The Biotech Growth Trust PLC Shareholders

Director/PDMR Dealings

Major Shareholding Notifications

The Biotech Growth Trust PLC Shareholders

Director and PDMR Dealings

Major Shareholding Notifications

Director/PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications