Alexa HendersonPurchase

25/08/2026101 shares£1,126.15

Kate Cornish-BowdenPurchase

25/08/2026233 shares£2,593.29

Kate Cornish-BowdenPurchase

27/01/2026265 shares£2,544.03

Alexa HendersonPurchase

27/01/2026115 shares£1,108.49

Date	Director/PDMR	Type	Shares	Price	Value
25/08/2026	Alexa Henderson	Purchase	101	1,115.00	£1,126.15
25/08/2026	Kate Cornish-Bowden	Purchase	233	1,113.00	£2,593.29
27/01/2026	Kate Cornish-Bowden	Purchase	265	960.01	£2,544.03
27/01/2026	Alexa Henderson	Purchase	115	963.90	£1,108.49

Open positions only

Northern Trust Global Services SE

23/07/20261,567,913 shares4.93%

Charles Stanley & Co. Limited

27/02/20251,789,225 shares5.02%

South Yorkshire Pensions Authority

31/07/20241,059,474 shares2.85%

Schroders plc

13/06/2024

South Yorkshire Pensions Authority

12/06/20241,405,000 shares3.76%

Schroders Plc

29/05/20241,454,736 shares3.88%

Charles Stanley Group Plc

15/03/20241,871,013 shares4.99%

Charles Stanley Group Plc

04/03/20241,916,393 shares5.00%

Charles Stanley Group Plc

01/03/20241,914,118 shares4.99%

Date	Shareholder	Shares Held	Percentage
23/07/2026	Northern Trust Global Services SE	1,567,913	4.93%
27/02/2025	Charles Stanley & Co. Limited	1,789,225	5.02%
31/07/2024	South Yorkshire Pensions Authority	1,059,474	2.85%
13/06/2024	Schroders plc	–	–
12/06/2024	South Yorkshire Pensions Authority	1,405,000	3.76%
29/05/2024	Schroders Plc	1,454,736	3.88%
15/03/2024	Charles Stanley Group Plc	1,871,013	4.99%
04/03/2024	Charles Stanley Group Plc	1,916,393	5.00%
01/03/2024	Charles Stanley Group Plc	1,914,118	4.99%

Alexa HendersonPurchase

25/08/2026101 shares£1,126.15

Kate Cornish-BowdenPurchase

25/08/2026233 shares£2,593.29

Kate Cornish-BowdenPurchase

27/01/2026265 shares£2,544.03

Alexa HendersonPurchase

27/01/2026115 shares£1,108.49

Date	Director/PDMR	Type	Shares	Price	Value
25/08/2026	Alexa Henderson	Purchase	101	1,115.00	£1,126.15
25/08/2026	Kate Cornish-Bowden	Purchase	233	1,113.00	£2,593.29
27/01/2026	Kate Cornish-Bowden	Purchase	265	960.01	£2,544.03
27/01/2026	Alexa Henderson	Purchase	115	963.90	£1,108.49

Open positions only

Northern Trust Global Services SE

23/07/20261,567,913 shares4.93%

Charles Stanley & Co. Limited

27/02/20251,789,225 shares5.02%

South Yorkshire Pensions Authority

31/07/20241,059,474 shares2.85%

Schroders plc

13/06/2024

South Yorkshire Pensions Authority

12/06/20241,405,000 shares3.76%

Schroders Plc

29/05/20241,454,736 shares3.88%

Charles Stanley Group Plc

15/03/20241,871,013 shares4.99%

Charles Stanley Group Plc

04/03/20241,916,393 shares5.00%

Charles Stanley Group Plc

01/03/20241,914,118 shares4.99%

Date	Shareholder	Shares Held	Percentage
23/07/2026	Northern Trust Global Services SE	1,567,913	4.93%
27/02/2025	Charles Stanley & Co. Limited	1,789,225	5.02%
31/07/2024	South Yorkshire Pensions Authority	1,059,474	2.85%
13/06/2024	Schroders plc	–	–
12/06/2024	South Yorkshire Pensions Authority	1,405,000	3.76%
29/05/2024	Schroders Plc	1,454,736	3.88%
15/03/2024	Charles Stanley Group Plc	1,871,013	4.99%
04/03/2024	Charles Stanley Group Plc	1,916,393	5.00%
01/03/2024	Charles Stanley Group Plc	1,914,118	4.99%

Alexa HendersonPurchase

25/08/2026101 shares£1,126.15

Kate Cornish-BowdenPurchase

25/08/2026233 shares£2,593.29

Kate Cornish-BowdenPurchase

27/01/2026265 shares£2,544.03

Alexa HendersonPurchase

27/01/2026115 shares£1,108.49

Date	Director/PDMR	Type	Shares	Price	Value
25/08/2026	Alexa Henderson	Purchase	101	1,115.00	£1,126.15
25/08/2026	Kate Cornish-Bowden	Purchase	233	1,113.00	£2,593.29
27/01/2026	Kate Cornish-Bowden	Purchase	265	960.01	£2,544.03
27/01/2026	Alexa Henderson	Purchase	115	963.90	£1,108.49

Open positions only

Northern Trust Global Services SE

23/07/20261,567,913 shares4.93%

Charles Stanley & Co. Limited

27/02/20251,789,225 shares5.02%

South Yorkshire Pensions Authority

31/07/20241,059,474 shares2.85%

Schroders plc

13/06/2024

South Yorkshire Pensions Authority

12/06/20241,405,000 shares3.76%

Schroders Plc

29/05/20241,454,736 shares3.88%

Charles Stanley Group Plc

15/03/20241,871,013 shares4.99%

Charles Stanley Group Plc

04/03/20241,916,393 shares5.00%

Charles Stanley Group Plc

01/03/20241,914,118 shares4.99%

Date	Shareholder	Shares Held	Percentage
23/07/2026	Northern Trust Global Services SE	1,567,913	4.93%
27/02/2025	Charles Stanley & Co. Limited	1,789,225	5.02%
31/07/2024	South Yorkshire Pensions Authority	1,059,474	2.85%
13/06/2024	Schroders plc	–	–
12/06/2024	South Yorkshire Pensions Authority	1,405,000	3.76%
29/05/2024	Schroders Plc	1,454,736	3.88%
15/03/2024	Charles Stanley Group Plc	1,871,013	4.99%
04/03/2024	Charles Stanley Group Plc	1,916,393	5.00%
01/03/2024	Charles Stanley Group Plc	1,914,118	4.99%

Alexa HendersonPurchase

25/08/2026101 shares£1,126.15

Kate Cornish-BowdenPurchase

25/08/2026233 shares£2,593.29

Kate Cornish-BowdenPurchase

27/01/2026265 shares£2,544.03

Alexa HendersonPurchase

27/01/2026115 shares£1,108.49

Date	Director/PDMR	Type	Shares	Price	Value
25/08/2026	Alexa Henderson	Purchase	101	1,115.00	£1,126.15
25/08/2026	Kate Cornish-Bowden	Purchase	233	1,113.00	£2,593.29
27/01/2026	Kate Cornish-Bowden	Purchase	265	960.01	£2,544.03
27/01/2026	Alexa Henderson	Purchase	115	963.90	£1,108.49

Open positions only

Northern Trust Global Services SE

23/07/20261,567,913 shares4.93%

Charles Stanley & Co. Limited

27/02/20251,789,225 shares5.02%

South Yorkshire Pensions Authority

31/07/20241,059,474 shares2.85%

Schroders plc

13/06/2024

South Yorkshire Pensions Authority

12/06/20241,405,000 shares3.76%

Schroders Plc

29/05/20241,454,736 shares3.88%

Charles Stanley Group Plc

15/03/20241,871,013 shares4.99%

Charles Stanley Group Plc

04/03/20241,916,393 shares5.00%

Charles Stanley Group Plc

01/03/20241,914,118 shares4.99%

Date	Shareholder	Shares Held	Percentage
23/07/2026	Northern Trust Global Services SE	1,567,913	4.93%
27/02/2025	Charles Stanley & Co. Limited	1,789,225	5.02%
31/07/2024	South Yorkshire Pensions Authority	1,059,474	2.85%
13/06/2024	Schroders plc	–	–
12/06/2024	South Yorkshire Pensions Authority	1,405,000	3.76%
29/05/2024	Schroders Plc	1,454,736	3.88%
15/03/2024	Charles Stanley Group Plc	1,871,013	4.99%
04/03/2024	Charles Stanley Group Plc	1,916,393	5.00%
01/03/2024	Charles Stanley Group Plc	1,914,118	4.99%

International Biotechnology Trust plc Shareholders

Director/PDMR Dealings

Major Shareholding Notifications

International Biotechnology Trust plc Shareholders

Director and PDMR Dealings

Major Shareholding Notifications

Director/PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications