John R. ShawSale

02/10/20265,000 shares$12,592.00

Peter NieuwenhuizenPurchase

05/05/20263,400 shares£3,717.90

Peter NieuwenhuizenPurchase

16/01/20268,000 shares£8,820.00

Date	Director/PDMR	Type	Shares	Price	Value
02/10/2026	John R. Shaw	Sale	5,000	$2.52	$12,592.00
05/05/2026	Peter Nieuwenhuizen	Purchase	3,400	109.35	£3,717.90
16/01/2026	Peter Nieuwenhuizen	Purchase	8,000	110.25	£8,820.00

John R. ShawSale

02/10/20265,000 shares$12,592.00

Peter NieuwenhuizenPurchase

05/05/20263,400 shares£3,717.90

Peter NieuwenhuizenPurchase

16/01/20268,000 shares£8,820.00

Date	Director/PDMR	Type	Shares	Price	Value
02/10/2026	John R. Shaw	Sale	5,000	$2.52	$12,592.00
05/05/2026	Peter Nieuwenhuizen	Purchase	3,400	109.35	£3,717.90
16/01/2026	Peter Nieuwenhuizen	Purchase	8,000	110.25	£8,820.00

John R. ShawSale

02/10/20265,000 shares$12,592.00

Peter NieuwenhuizenPurchase

05/05/20263,400 shares£3,717.90

Peter NieuwenhuizenPurchase

16/01/20268,000 shares£8,820.00

Date	Director/PDMR	Type	Shares	Price	Value
02/10/2026	John R. Shaw	Sale	5,000	$2.52	$12,592.00
05/05/2026	Peter Nieuwenhuizen	Purchase	3,400	109.35	£3,717.90
16/01/2026	Peter Nieuwenhuizen	Purchase	8,000	110.25	£8,820.00

Open positions only

Octopus Investments Limited

28/01/20261,188,646 shares8.81%

Octopus Investments Limited

27/08/20251,327,146 shares9.84%

Maven Renovar VCT PLC

06/05/2025784,313 shares5.82%

IP Group plc

02/03/202355,913,194 shares8.29%

Octopus Investments Limited

28/02/202372,357,399 shares10.73%

Canaccord Genuity Group Inc.

28/02/202360,255,167 shares8.94%

Amati AIM VCT plc

28/02/202339,215,687 shares5.81%

Octopus Investments Limited

23/02/202337,295,917 shares6.96%

Date	Shareholder	Shares Held	Percentage
28/01/2026	Octopus Investments Limited	1,188,646	8.81%
27/08/2025	Octopus Investments Limited	1,327,146	9.84%
06/05/2025	Maven Renovar VCT PLC	784,313	5.82%
02/03/2023	IP Group plc	55,913,194	8.29%
28/02/2023	Octopus Investments Limited	72,357,399	10.73%
28/02/2023	Canaccord Genuity Group Inc.	60,255,167	8.94%
28/02/2023	Amati AIM VCT plc	39,215,687	5.81%
23/02/2023	Octopus Investments Limited	37,295,917	6.96%

John R. ShawSale

02/10/20265,000 shares$12,592.00

Peter NieuwenhuizenPurchase

05/05/20263,400 shares£3,717.90

Peter NieuwenhuizenPurchase

16/01/20268,000 shares£8,820.00

Date	Director/PDMR	Type	Shares	Price	Value
02/10/2026	John R. Shaw	Sale	5,000	$2.52	$12,592.00
05/05/2026	Peter Nieuwenhuizen	Purchase	3,400	109.35	£3,717.90
16/01/2026	Peter Nieuwenhuizen	Purchase	8,000	110.25	£8,820.00

Open positions only

Octopus Investments Limited

28/01/20261,188,646 shares8.81%

Octopus Investments Limited

27/08/20251,327,146 shares9.84%

Maven Renovar VCT PLC

06/05/2025784,313 shares5.82%

IP Group plc

02/03/202355,913,194 shares8.29%

Octopus Investments Limited

28/02/202372,357,399 shares10.73%

Canaccord Genuity Group Inc.

28/02/202360,255,167 shares8.94%

Amati AIM VCT plc

28/02/202339,215,687 shares5.81%

Octopus Investments Limited

23/02/202337,295,917 shares6.96%

Date	Shareholder	Shares Held	Percentage
28/01/2026	Octopus Investments Limited	1,188,646	8.81%
27/08/2025	Octopus Investments Limited	1,327,146	9.84%
06/05/2025	Maven Renovar VCT PLC	784,313	5.82%
02/03/2023	IP Group plc	55,913,194	8.29%
28/02/2023	Octopus Investments Limited	72,357,399	10.73%
28/02/2023	Canaccord Genuity Group Inc.	60,255,167	8.94%
28/02/2023	Amati AIM VCT plc	39,215,687	5.81%
23/02/2023	Octopus Investments Limited	37,295,917	6.96%

Open positions only

Octopus Investments Limited

28/01/20261,188,646 shares8.81%

Octopus Investments Limited

27/08/20251,327,146 shares9.84%

Maven Renovar VCT PLC

06/05/2025784,313 shares5.82%

IP Group plc

02/03/202355,913,194 shares8.29%

Octopus Investments Limited

28/02/202372,357,399 shares10.73%

Canaccord Genuity Group Inc.

28/02/202360,255,167 shares8.94%

Amati AIM VCT plc

28/02/202339,215,687 shares5.81%

Octopus Investments Limited

23/02/202337,295,917 shares6.96%

Date	Shareholder	Shares Held	Percentage
28/01/2026	Octopus Investments Limited	1,188,646	8.81%
27/08/2025	Octopus Investments Limited	1,327,146	9.84%
06/05/2025	Maven Renovar VCT PLC	784,313	5.82%
02/03/2023	IP Group plc	55,913,194	8.29%
28/02/2023	Octopus Investments Limited	72,357,399	10.73%
28/02/2023	Canaccord Genuity Group Inc.	60,255,167	8.94%
28/02/2023	Amati AIM VCT plc	39,215,687	5.81%
23/02/2023	Octopus Investments Limited	37,295,917	6.96%

Open positions only

Octopus Investments Limited

28/01/20261,188,646 shares8.81%

Octopus Investments Limited

27/08/20251,327,146 shares9.84%

Maven Renovar VCT PLC

06/05/2025784,313 shares5.82%

IP Group plc

02/03/202355,913,194 shares8.29%

Octopus Investments Limited

28/02/202372,357,399 shares10.73%

Canaccord Genuity Group Inc.

28/02/202360,255,167 shares8.94%

Amati AIM VCT plc

28/02/202339,215,687 shares5.81%

Octopus Investments Limited

23/02/202337,295,917 shares6.96%

Date	Shareholder	Shares Held	Percentage
28/01/2026	Octopus Investments Limited	1,188,646	8.81%
27/08/2025	Octopus Investments Limited	1,327,146	9.84%
06/05/2025	Maven Renovar VCT PLC	784,313	5.82%
02/03/2023	IP Group plc	55,913,194	8.29%
28/02/2023	Octopus Investments Limited	72,357,399	10.73%
28/02/2023	Canaccord Genuity Group Inc.	60,255,167	8.94%
28/02/2023	Amati AIM VCT plc	39,215,687	5.81%
23/02/2023	Octopus Investments Limited	37,295,917	6.96%

Itaconix plc Shareholders

Director/PDMR Dealings

Major Shareholding Notifications

Itaconix plc Shareholders

Director and PDMR Dealings

Major Shareholding Notifications

Director/PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Major Shareholding Notifications

Major Shareholding Notifications