8 October 2021

Oxford Nanopore Technologies plc (the "Company")

Total Voting Rights

In accordance with the Financial Conduct Authority's Disclosure, Guidance and Transparency Rules 5.6.1A, the Company announces that as at the date of this announcement, the Company's issued share capital consists of 813,170,521 ordinary shares of £0.0001 each, all with voting rights.  The Company holds no ordinary shares in Treasury.

The above figure may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the Disclosure, Guidance and Transparency Rules.

For further information, please contact:

Oxford Nanopore Technologies plc

[email protected]

Tulchan Group (communications adviser to the Company)

Tom Murray, Olivia Peters, Deborah Roney

+44 (0) 20 7353 4200     [email protected]