05 June 2025

Oxford Nanopore Technologies plc

(the "Company")

Changes in Composition of the Remuneration Committee

The Company is pleased to announce that Heather Preston has been appointed as Chair of the Remuneration Committee with immediate effect. Heather has been a Non-Executive Director of the Company since 19 December 2023 and is also a member of the Nomination Committee.

Heather succeeds John O'Higgins who stands down as Interim Chair of the Remuneration Committee but remains a Remuneration Committee, Nomination Committee, and Audit & Risk Committee member. The Board would like to thank John O'Higgins for his wise counsel and committed leadership in this role from 10 June 2024 to date.

This announcement has been made pursuant to the UK Listing Rule 6.4.6R.

-ENDS-

For further information please contact:

cosec@nanoporetech.com

ir@nanoporetech.com

About Oxford Nanopore Technologies plc:

Oxford Nanopore Technologies' goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology for faster, information rich, accessible and affordable molecular analysis. The first application is DNA/RNA sequencing, and the technology is in development for the analysis of other types of molecules including proteins. The technology is used in more than 125 countries to understand and characterise the biology of humans and diseases such as cancer, plants, animals, bacteria, viruses, and whole environments. Oxford Nanopore Technologies products are intended for molecular biology applications and are not intended for diagnostic purposes. For more information, please visit: https://nanoporetech.com/