Clive WhileyPurchase21/09/2026200,000 shares£83,000.00Darren FisherSale10/04/2025Darren FisherPurchase03/06/20242,781 shares£2,319.35Darren FisherSale23/05/202431,638 shares£24,772.55Darren FisherExercise23/05/202467,076 shares£0.00Jim MullenAward08/05/20241,311,004 shares£0.00Darren FisherAward08/05/2024801,980 shares£0.00DateDirector/PDMRTypeSharesPriceValue21/09/2026Clive WhileyPurchase200,00041.50£83,000.0010/04/2025Darren FisherSale–––03/06/2024Darren FisherPurchase2,78183.40£2,319.3523/05/2024Darren FisherSale31,63878.30£24,772.5523/05/2024Darren FisherExercise67,0760.00£0.0008/05/2024Jim MullenAward1,311,0040.00£0.0008/05/2024Darren FisherAward801,9800.00£0.00
Open positions onlyThe Wellcome Trust Limited as trustee of The Wellcome Trust07/08/202618,804,924 shares5.91%FMR LLC18/09/202515,474,412 shares4.86%Lombard Odier Asset Management (Europe) Limited05/06/202431,616,267 shares9.94%The Wellcome Trust Limited as trustee of The Wellcome Trust16/05/202415,958,396 shares5.02%FMR LLC29/09/202316,057,004 shares5.05%Lombard Odier Asset Management (Europe) Limited17/08/202315,955,434 shares5.02%Aberforth Partners LLP13/01/202331,795,824 shares10.03%The Wellcome Trust Limited as trustee of The Wellcome Trust12/01/202313,044,412 shares4.11%DateShareholderShares HeldPercentage07/08/2026The Wellcome Trust Limited as trustee of The Wellcome Trust18,804,9245.91%18/09/2025FMR LLC15,474,4124.86%05/06/2024Lombard Odier Asset Management (Europe) Limited31,616,2679.94%16/05/2024The Wellcome Trust Limited as trustee of The Wellcome Trust15,958,3965.02%29/09/2023FMR LLC16,057,0045.05%17/08/2023Lombard Odier Asset Management (Europe) Limited15,955,4345.02%13/01/2023Aberforth Partners LLP31,795,82410.03%12/01/2023The Wellcome Trust Limited as trustee of The Wellcome Trust13,044,4124.11%
Clive WhileyPurchase21/09/2026200,000 shares£83,000.00Darren FisherSale10/04/2025Darren FisherPurchase03/06/20242,781 shares£2,319.35Darren FisherSale23/05/202431,638 shares£24,772.55Darren FisherExercise23/05/202467,076 shares£0.00Jim MullenAward08/05/20241,311,004 shares£0.00Darren FisherAward08/05/2024801,980 shares£0.00DateDirector/PDMRTypeSharesPriceValue21/09/2026Clive WhileyPurchase200,00041.50£83,000.0010/04/2025Darren FisherSale–––03/06/2024Darren FisherPurchase2,78183.40£2,319.3523/05/2024Darren FisherSale31,63878.30£24,772.5523/05/2024Darren FisherExercise67,0760.00£0.0008/05/2024Jim MullenAward1,311,0040.00£0.0008/05/2024Darren FisherAward801,9800.00£0.00
Open positions onlyThe Wellcome Trust Limited as trustee of The Wellcome Trust07/08/202618,804,924 shares5.91%FMR LLC18/09/202515,474,412 shares4.86%Lombard Odier Asset Management (Europe) Limited05/06/202431,616,267 shares9.94%The Wellcome Trust Limited as trustee of The Wellcome Trust16/05/202415,958,396 shares5.02%FMR LLC29/09/202316,057,004 shares5.05%Lombard Odier Asset Management (Europe) Limited17/08/202315,955,434 shares5.02%Aberforth Partners LLP13/01/202331,795,824 shares10.03%The Wellcome Trust Limited as trustee of The Wellcome Trust12/01/202313,044,412 shares4.11%DateShareholderShares HeldPercentage07/08/2026The Wellcome Trust Limited as trustee of The Wellcome Trust18,804,9245.91%18/09/2025FMR LLC15,474,4124.86%05/06/2024Lombard Odier Asset Management (Europe) Limited31,616,2679.94%16/05/2024The Wellcome Trust Limited as trustee of The Wellcome Trust15,958,3965.02%29/09/2023FMR LLC16,057,0045.05%17/08/2023Lombard Odier Asset Management (Europe) Limited15,955,4345.02%13/01/2023Aberforth Partners LLP31,795,82410.03%12/01/2023The Wellcome Trust Limited as trustee of The Wellcome Trust13,044,4124.11%
