Syncona Limited (SYNC) Share Price & Analysis

Open: 123.90
High: 126.00
Low: 123.06
Close: 123.96
Change: +0.20 (0.16%)
Volume: 52,313

1M Performance: +8.2%
3M Performance: +14.0%
1Y Performance: +0.2%
Market Cap: £834m
Avg Daily Volume: 563.2K

52-Week Range

86.90(10 Apr 26)124.40(6 Oct 26)

Current 123.96 · position in 52-week range

Profit After Tax:	-£143.2M
Total Assets:	£1.1B
Shareholders' Equity:	£1.1B
Operating Cash Flow:	£43.9M

As at Mar 20255 years of data

Going concern: Material uncertainty
Principal risks: 12

29 Sept 2026	07:00:08	SIML announces changes to leadership team
24 Sept 2026	12:00:01	Holding(s) in Company
23 Sept 2026	08:30:00	Holding(s) in Company
21 Sept 2026	07:00:10	Beacon delivers positive topline PII/III results
17 Sept 2026	16:30:06	Holding(s) in Company

2 Jul 2025	Annual Report and Accounts 2025
4 Jul 2024	Annual Report and Accounts 2024
28 Jun 2023	Annual Report and Accounts 2023

Melanie GeeChair

–

Kenneth GalbraithChair of SIML and Executive Partner

–

Kate ButlerChief Financial Officer

–

Harriet Gower IsaacChief People Officer

–

Gian Piero ReverberiNon-Executive Director

8 yrs 6 mos

Syncona Limited invests in and develops companies within the biotechnology and healthcare sectors, focusing on therapies that address significant medical challenges. Its investment objective is to support businesses that aim to improve and prolong human life. The trust operates primarily in the life sciences sector, making it a peer of other trusts with similar mandates and geographic focus.

Industry: Financials
Sector: Financial Services
LEI: 213800X8MBI5VQITLW60
Issuer: Syncona Limited
Region: Europe
Admission date: 26 Oct 2012
Website: www.synconaltd.com
X: @SynconaLtd

Dividend yield: 0.00%
EPS: -22.5p

Based on FY2025 reported figures (GBP).

NAV per Share: 170.60p
Discount/Premium: -27.3%
Total Net Assets: £1.04bn

Shares in issueas at 3 Aug 2026: 672,558,750
Total Voting Rights: 608,202,354
Treasury Shares: 64,356,396

Last updated: 7 October 2026

Net-zero target: 2050

18/06/2025

112,500£99,928

17/06/2025

110,000£97,482

16/06/2025

111,050£99,714

13/06/2025

61,671£53,876

12/06/2025

113,500£98,824

Latest year: FY25
Dividend: No dividend declared

ISIN: GG00B8P59C08
Exchange: XLON
Market: Main Market
Market Segment: STMM
Market Sector: F25F
Security Description: Ordinary Shares of No Par Value; fully paid
Listing Category: Closed-ended investment funds

Open: 123.90
High: 126.00
Low: 123.06
Close: 123.96
Change: +0.20 (0.16%)
Volume: 52,313

1M Performance: +8.2%
3M Performance: +14.0%
1Y Performance: +0.2%
Market Cap: £834m
Avg Daily Volume: 563.2K

52-Week Range

86.90(10 Apr 26)124.40(6 Oct 26)

Current 123.96 · position in 52-week range

Profit After Tax:	-£143.2M
Total Assets:	£1.1B
Shareholders' Equity:	£1.1B
Operating Cash Flow:	£43.9M

As at Mar 20255 years of data

Going concern: Material uncertainty
Principal risks: 12

29 Sept 2026	07:00:08	SIML announces changes to leadership team
24 Sept 2026	12:00:01	Holding(s) in Company
23 Sept 2026	08:30:00	Holding(s) in Company
21 Sept 2026	07:00:10	Beacon delivers positive topline PII/III results
17 Sept 2026	16:30:06	Holding(s) in Company

2 Jul 2025	Annual Report and Accounts 2025
4 Jul 2024	Annual Report and Accounts 2024
28 Jun 2023	Annual Report and Accounts 2023

Melanie GeeChair

–

Kenneth GalbraithChair of SIML and Executive Partner

–

Kate ButlerChief Financial Officer

–

Harriet Gower IsaacChief People Officer

–

Gian Piero ReverberiNon-Executive Director

8 yrs 6 mos

Industry: Financials
Sector: Financial Services
LEI: 213800X8MBI5VQITLW60
Issuer: Syncona Limited
Region: Europe
Admission date: 26 Oct 2012
Website: www.synconaltd.com
X: @SynconaLtd

Dividend yield: 0.00%
EPS: -22.5p

Based on FY2025 reported figures (GBP).

NAV per Share: 170.60p
Discount/Premium: -27.3%
Total Net Assets: £1.04bn

Shares in issueas at 3 Aug 2026: 672,558,750
Total Voting Rights: 608,202,354
Treasury Shares: 64,356,396

Last updated: 7 October 2026

Net-zero target: 2050

18/06/2025

112,500£99,928

17/06/2025

110,000£97,482

16/06/2025

111,050£99,714

13/06/2025

61,671£53,876

12/06/2025

113,500£98,824

Latest year: FY25
Dividend: No dividend declared

ISIN: GG00B8P59C08
Exchange: XLON
Market: Main Market
Market Segment: STMM
Market Sector: F25F
Security Description: Ordinary Shares of No Par Value; fully paid
Listing Category: Closed-ended investment funds

Open: 123.90
High: 126.00
Low: 123.06
Close: 123.96
Change: +0.20 (0.16%)
Volume: 52,313

1M Performance: +8.2%
3M Performance: +14.0%
1Y Performance: +0.2%
Market Cap: £834m
Avg Daily Volume: 563.2K

52-Week Range

86.90(10 Apr 26)124.40(6 Oct 26)

Current 123.96 · position in 52-week range

Profit After Tax:	-£143.2M
Total Assets:	£1.1B
Shareholders' Equity:	£1.1B
Operating Cash Flow:	£43.9M

As at Mar 20255 years of data

Going concern: Material uncertainty
Principal risks: 12

29 Sept 2026	07:00:08	SIML announces changes to leadership team
24 Sept 2026	12:00:01	Holding(s) in Company
23 Sept 2026	08:30:00	Holding(s) in Company
21 Sept 2026	07:00:10	Beacon delivers positive topline PII/III results
17 Sept 2026	16:30:06	Holding(s) in Company

2 Jul 2025	Annual Report and Accounts 2025
4 Jul 2024	Annual Report and Accounts 2024
28 Jun 2023	Annual Report and Accounts 2023

Melanie GeeChair

–

Kenneth GalbraithChair of SIML and Executive Partner

–

Kate ButlerChief Financial Officer

–

Harriet Gower IsaacChief People Officer

–

Gian Piero ReverberiNon-Executive Director

8 yrs 6 mos

Industry: Financials
Sector: Financial Services
LEI: 213800X8MBI5VQITLW60
Issuer: Syncona Limited
Region: Europe
Admission date: 26 Oct 2012
Website: www.synconaltd.com
X: @SynconaLtd

Dividend yield: 0.00%
EPS: -22.5p

Based on FY2025 reported figures (GBP).

Issuer	Mkt cap	1Y
RCP RIT Capital Partners PLC	£3.05bn	+0.2%
PPET Patria Private Equity Trust PLC	£870m	+0.1%
OCI Oakley Capital Investments Limited	£840m	-0.1%
SYNCSyncona Limited	£834m	+0.2%
GSCT The Global Smaller Companies Trust plc	£780m	+0.1%
BGUK Baillie Gifford UK Growth Trust PLC	£211m	+0.1%

Peers in Financial Services, ranked by comparable market cap. 1Y = trailing share-price change.

NAV per Share: 170.60p
Discount/Premium: -27.3%
Total Net Assets: £1.04bn

Shares in issueas at 3 Aug 2026: 672,558,750
Total Voting Rights: 608,202,354
Treasury Shares: 64,356,396

Last updated: 7 October 2026

Net-zero target: 2050

18/06/2025

112,500£99,928

17/06/2025

110,000£97,482

16/06/2025

111,050£99,714

13/06/2025

61,671£53,876

12/06/2025

113,500£98,824

Latest year: FY25
Dividend: No dividend declared

ISIN: GG00B8P59C08
Exchange: XLON
Market: Main Market
Market Segment: STMM
Market Sector: F25F
Security Description: Ordinary Shares of No Par Value; fully paid
Listing Category: Closed-ended investment funds

Open: 123.90
High: 126.00
Low: 123.06
Close: 123.96
Change: +0.20 (0.16%)
Volume: 52,313

1M Performance: +8.2%
3M Performance: +14.0%
1Y Performance: +0.2%
Market Cap: £834m
Avg Daily Volume: 563.2K

52-Week Range

86.90(10 Apr 26)124.40(6 Oct 26)

Current 123.96 · position in 52-week range

Profit After Tax:	-£143.2M
Total Assets:	£1.1B
Shareholders' Equity:	£1.1B
Operating Cash Flow:	£43.9M

As at Mar 20255 years of data

Going concern: Material uncertainty
Principal risks: 12

29 Sept 2026	07:00:08	SIML announces changes to leadership team
24 Sept 2026	12:00:01	Holding(s) in Company
23 Sept 2026	08:30:00	Holding(s) in Company
21 Sept 2026	07:00:10	Beacon delivers positive topline PII/III results
17 Sept 2026	16:30:06	Holding(s) in Company

2 Jul 2025	Annual Report and Accounts 2025
4 Jul 2024	Annual Report and Accounts 2024
28 Jun 2023	Annual Report and Accounts 2023

Melanie GeeChair

–

Kenneth GalbraithChair of SIML and Executive Partner

–

Kate ButlerChief Financial Officer

–

Harriet Gower IsaacChief People Officer

–

Gian Piero ReverberiNon-Executive Director

8 yrs 6 mos

Industry: Financials
Sector: Financial Services
LEI: 213800X8MBI5VQITLW60
Issuer: Syncona Limited
Region: Europe
Admission date: 26 Oct 2012
Website: www.synconaltd.com
X: @SynconaLtd

Dividend yield: 0.00%
EPS: -22.5p

Based on FY2025 reported figures (GBP).

Issuer	Mkt cap	1Y
RCP RIT Capital Partners PLC	£3.05bn	+0.2%
PPET Patria Private Equity Trust PLC	£870m	+0.1%
OCI Oakley Capital Investments Limited	£840m	-0.1%
SYNCSyncona Limited	£834m	+0.2%
GSCT The Global Smaller Companies Trust plc	£780m	+0.1%
BGUK Baillie Gifford UK Growth Trust PLC	£211m	+0.1%

Peers in Financial Services, ranked by comparable market cap. 1Y = trailing share-price change.

NAV per Share: 170.60p
Discount/Premium: -27.3%
Total Net Assets: £1.04bn

Shares in issueas at 3 Aug 2026: 672,558,750
Total Voting Rights: 608,202,354
Treasury Shares: 64,356,396

Last updated: 7 October 2026

Net-zero target: 2050

18/06/2025

112,500£99,928

17/06/2025

110,000£97,482

16/06/2025

111,050£99,714

13/06/2025

61,671£53,876

12/06/2025

113,500£98,824

Latest year: FY25
Dividend: No dividend declared

ISIN: GG00B8P59C08
Exchange: XLON
Market: Main Market
Market Segment: STMM
Market Sector: F25F
Security Description: Ordinary Shares of No Par Value; fully paid
Listing Category: Closed-ended investment funds

Issuer	Mkt cap	1Y
RCP RIT Capital Partners PLC	£3.05bn	+0.2%
PPET Patria Private Equity Trust PLC	£870m	+0.1%
OCI Oakley Capital Investments Limited	£840m	-0.1%
SYNCSyncona Limited	£834m	+0.2%
GSCT The Global Smaller Companies Trust plc	£780m	+0.1%
BGUK Baillie Gifford UK Growth Trust PLC	£211m	+0.1%

Peers in Financial Services, ranked by comparable market cap. 1Y = trailing share-price change.

Issuer	Mkt cap	1Y
RCP RIT Capital Partners PLC	£3.05bn	+0.2%
PPET Patria Private Equity Trust PLC	£870m	+0.1%
OCI Oakley Capital Investments Limited	£840m	-0.1%
SYNCSyncona Limited	£834m	+0.2%
GSCT The Global Smaller Companies Trust plc	£780m	+0.1%
BGUK Baillie Gifford UK Growth Trust PLC	£211m	+0.1%

Peers in Financial Services, ranked by comparable market cap. 1Y = trailing share-price change.

1 Oct 2026	Syncona Limited (SYNC.L) Stock Analysis: A 63% Potential Upside Amidst Healthcare Investment Focus	DirectorsTalk Interviews
29 Sept 2026	Syncona hires ex-NICE chief Dr Sam Roberts to steer its life science start-ups to profitability	QuotedData
29 Sept 2026	Syncona strengthens leadership to drive portfolio value creation	DirectorsTalk Interviews
21 Sept 2026	Syncona’s Beacon Therapeutics delivers positive pivotal trial result	QuotedData
24 Aug 2026	Morning briefing: Saba lifts Syncona stake; Jupiter trims HgCapital position	QuotedData
6 Aug 2026	Syncona Limited (SYNC.L): Analyst Consensus Signals a Striking 90.57% Upside Potential	DirectorsTalk Interviews
16 Jul 2026	SYNCONA LIMITED ORD NPV (SYNC.L)	DirectorsTalk Interviews
22 Jun 2026	Director dealings: Syncona non-executive director snaps up shares	ShareCast

1 Oct 2026	Syncona Limited (SYNC.L) Stock Analysis: A 63% Potential Upside Amidst Healthcare Investment Focus	DirectorsTalk Interviews
29 Sept 2026	Syncona hires ex-NICE chief Dr Sam Roberts to steer its life science start-ups to profitability	QuotedData
29 Sept 2026	Syncona strengthens leadership to drive portfolio value creation	DirectorsTalk Interviews
21 Sept 2026	Syncona’s Beacon Therapeutics delivers positive pivotal trial result	QuotedData
24 Aug 2026	Morning briefing: Saba lifts Syncona stake; Jupiter trims HgCapital position	QuotedData
6 Aug 2026	Syncona Limited (SYNC.L): Analyst Consensus Signals a Striking 90.57% Upside Potential	DirectorsTalk Interviews
16 Jul 2026	SYNCONA LIMITED ORD NPV (SYNC.L)	DirectorsTalk Interviews
22 Jun 2026	Director dealings: Syncona non-executive director snaps up shares	ShareCast

1 Oct 2026	Syncona Limited (SYNC.L) Stock Analysis: A 63% Potential Upside Amidst Healthcare Investment Focus	DirectorsTalk Interviews
29 Sept 2026	Syncona hires ex-NICE chief Dr Sam Roberts to steer its life science start-ups to profitability	QuotedData
29 Sept 2026	Syncona strengthens leadership to drive portfolio value creation	DirectorsTalk Interviews
21 Sept 2026	Syncona’s Beacon Therapeutics delivers positive pivotal trial result	QuotedData
24 Aug 2026	Morning briefing: Saba lifts Syncona stake; Jupiter trims HgCapital position	QuotedData
6 Aug 2026	Syncona Limited (SYNC.L): Analyst Consensus Signals a Striking 90.57% Upside Potential	DirectorsTalk Interviews
16 Jul 2026	SYNCONA LIMITED ORD NPV (SYNC.L)	DirectorsTalk Interviews
22 Jun 2026	Director dealings: Syncona non-executive director snaps up shares	ShareCast

1 Oct 2026	Syncona Limited (SYNC.L) Stock Analysis: A 63% Potential Upside Amidst Healthcare Investment Focus	DirectorsTalk Interviews
29 Sept 2026	Syncona hires ex-NICE chief Dr Sam Roberts to steer its life science start-ups to profitability	QuotedData
29 Sept 2026	Syncona strengthens leadership to drive portfolio value creation	DirectorsTalk Interviews
21 Sept 2026	Syncona’s Beacon Therapeutics delivers positive pivotal trial result	QuotedData
24 Aug 2026	Morning briefing: Saba lifts Syncona stake; Jupiter trims HgCapital position	QuotedData
6 Aug 2026	Syncona Limited (SYNC.L): Analyst Consensus Signals a Striking 90.57% Upside Potential	DirectorsTalk Interviews
16 Jul 2026	SYNCONA LIMITED ORD NPV (SYNC.L)	DirectorsTalk Interviews
22 Jun 2026	Director dealings: Syncona non-executive director snaps up shares	ShareCast