Lachlan SmithPurchase

02/05/202520,228 shares£2,399.04

Date	Director/PDMR	Type	Shares	Price	Value
02/05/2025	Lachlan Smith	Purchase	20,228	11.86	£2,399.04

Open positions only

Dowgate Group Limited

02/06/20263,072,254 shares4.95%

Rathbones Investment Management Ltd

21/12/20234,142,301 shares6.67%

Amati AIM VCT plc

21/12/2023775,586 shares1.24%

Dowgate Capital Limited

19/12/20236,029,094 shares9.71%

MARK BRADSHAW

10/11/202322,184,798 shares3.61%

Date	Shareholder	Shares Held	Percentage
02/06/2026	Dowgate Group Limited	3,072,254	4.95%
21/12/2023	Rathbones Investment Management Ltd	4,142,301	6.67%
21/12/2023	Amati AIM VCT plc	775,586	1.24%
19/12/2023	Dowgate Capital Limited	6,029,094	9.71%
10/11/2023	MARK BRADSHAW	22,184,798	3.61%

Lachlan SmithPurchase

02/05/202520,228 shares£2,399.04

Date	Director/PDMR	Type	Shares	Price	Value
02/05/2025	Lachlan Smith	Purchase	20,228	11.86	£2,399.04

Lachlan SmithPurchase

02/05/202520,228 shares£2,399.04

Date	Director/PDMR	Type	Shares	Price	Value
02/05/2025	Lachlan Smith	Purchase	20,228	11.86	£2,399.04

Open positions only

Dowgate Group Limited

02/06/20263,072,254 shares4.95%

Rathbones Investment Management Ltd

21/12/20234,142,301 shares6.67%

Amati AIM VCT plc

21/12/2023775,586 shares1.24%

Dowgate Capital Limited

19/12/20236,029,094 shares9.71%

MARK BRADSHAW

10/11/202322,184,798 shares3.61%

Date	Shareholder	Shares Held	Percentage
02/06/2026	Dowgate Group Limited	3,072,254	4.95%
21/12/2023	Rathbones Investment Management Ltd	4,142,301	6.67%
21/12/2023	Amati AIM VCT plc	775,586	1.24%
19/12/2023	Dowgate Capital Limited	6,029,094	9.71%
10/11/2023	MARK BRADSHAW	22,184,798	3.61%

Lachlan SmithPurchase

02/05/202520,228 shares£2,399.04

Date	Director/PDMR	Type	Shares	Price	Value
02/05/2025	Lachlan Smith	Purchase	20,228	11.86	£2,399.04

Open positions only

Dowgate Group Limited

02/06/20263,072,254 shares4.95%

Rathbones Investment Management Ltd

21/12/20234,142,301 shares6.67%

Amati AIM VCT plc

21/12/2023775,586 shares1.24%

Dowgate Capital Limited

19/12/20236,029,094 shares9.71%

MARK BRADSHAW

10/11/202322,184,798 shares3.61%

Date	Shareholder	Shares Held	Percentage
02/06/2026	Dowgate Group Limited	3,072,254	4.95%
21/12/2023	Rathbones Investment Management Ltd	4,142,301	6.67%
21/12/2023	Amati AIM VCT plc	775,586	1.24%
19/12/2023	Dowgate Capital Limited	6,029,094	9.71%
10/11/2023	MARK BRADSHAW	22,184,798	3.61%

Open positions only

Dowgate Group Limited

02/06/20263,072,254 shares4.95%

Rathbones Investment Management Ltd

21/12/20234,142,301 shares6.67%

Amati AIM VCT plc

21/12/2023775,586 shares1.24%

Dowgate Capital Limited

19/12/20236,029,094 shares9.71%

MARK BRADSHAW

10/11/202322,184,798 shares3.61%

Date	Shareholder	Shares Held	Percentage
02/06/2026	Dowgate Group Limited	3,072,254	4.95%
21/12/2023	Rathbones Investment Management Ltd	4,142,301	6.67%
21/12/2023	Amati AIM VCT plc	775,586	1.24%
19/12/2023	Dowgate Capital Limited	6,029,094	9.71%
10/11/2023	MARK BRADSHAW	22,184,798	3.61%

RUA Life Sciences PLC Shareholders

Director and PDMR Dealings

Major Shareholding Notifications

RUA Life Sciences PLC Shareholders

Director and PDMR Dealings

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Director and PDMR Dealings

Major Shareholding Notifications

Major Shareholding Notifications

Major Shareholding Notifications