Matt WebbSale02/10/202616,312 shares£329,910.20Louise WebbPurchase02/10/202616,312 shares£329,910.20Matt WebbSale02/10/202616,312 shares£329,910.20Louise WebbPurchase02/10/202616,312 shares£329,910.20Jamie PikePurchase04/03/20267,496 shares£74.96Charlotta GinmanPurchase03/03/20261,515 shares£15.15Gavin GriggsSale16/12/20253,002 shares£27,138.08Gavin GriggsExercise16/12/20256,371 shares£0.00Daniel ShookPurchase24/10/2025768 shares£7,972.45Daniel ShookPurchase22/10/20251,103 shares£11,444.73DateDirector/PDMRTypeSharesPriceValue02/10/2026Matt WebbSale16,3122,022.00£329,910.2002/10/2026Louise WebbPurchase16,3122,022.00£329,910.2002/10/2026Matt WebbSale16,3122,022.00£329,910.2002/10/2026Louise WebbPurchase16,3122,022.00£329,910.2004/03/2026Jamie PikePurchase7,4961.00£74.9603/03/2026Charlotta GinmanPurchase1,5151.00£15.1516/12/2025Gavin GriggsSale3,002904.00£27,138.0816/12/2025Gavin GriggsExercise6,3710.00£0.0024/10/2025Daniel ShookPurchase7681,038.08£7,972.4522/10/2025Daniel ShookPurchase1,1031,037.60£11,444.73
Open positions onlyAberdeen Group plc28/09/20261,413,626 shares5.04%Aberdeen Group plc28/09/20261,413,626 shares5.04%The Wellcome Trust Limited as trustee of The Wellcome Trust07/08/20261,379,123 shares4.92%Ameriprise Financial, Inc.22/05/20261,377,513 shares4.91%JPMorgan Asset Management Holdings Inc.07/05/20261,434,191 shares5.12%Ameriprise Financial, Inc.05/05/20261,434,836 shares5.12%Odyssean Investment Trust PLC30/04/20262,650,000 shares9.45%Ameriprise Financial, Inc.08/12/20251,395,278 shares4.98%Ameriprise Financial, Inc.13/10/20251,443,565 shares5.15%JANUS HENDERSON GROUP PLC24/09/20251,383,854 shares4.94%The Wellcome Trust Limited as trustee of The Wellcome Trust14/08/20251,796,317 shares6.43%Ameriprise Financial, Inc.02/05/20251,377,148 shares4.93%Odyssean Investment Trust PLC24/04/20252,950,000 shares10.56%Aberforth Partners LLP22/04/20252,814,839 shares10.08%DateShareholderShares HeldPercentage28/09/2026Aberdeen Group plc1,413,6265.04%28/09/2026Aberdeen Group plc1,413,6265.04%07/08/2026The Wellcome Trust Limited as trustee of The Wellcome Trust1,379,1234.92%22/05/2026Ameriprise Financial, Inc.1,377,5134.91%07/05/2026JPMorgan Asset Management Holdings Inc.1,434,1915.12%05/05/2026Ameriprise Financial, Inc.1,434,8365.12%30/04/2026Odyssean Investment Trust PLC2,650,0009.45%08/12/2025Ameriprise Financial, Inc.1,395,2784.98%13/10/2025Ameriprise Financial, Inc.1,443,5655.15%24/09/2025JANUS HENDERSON GROUP PLC1,383,8544.94%14/08/2025The Wellcome Trust Limited as trustee of The Wellcome Trust1,796,3176.43%02/05/2025Ameriprise Financial, Inc.1,377,1484.93%24/04/2025Odyssean Investment Trust PLC2,950,00010.56%22/04/2025Aberforth Partners LLP2,814,83910.08%
Matt WebbSale02/10/202616,312 shares£329,910.20Louise WebbPurchase02/10/202616,312 shares£329,910.20Matt WebbSale02/10/202616,312 shares£329,910.20Louise WebbPurchase02/10/202616,312 shares£329,910.20Jamie PikePurchase04/03/20267,496 shares£74.96Charlotta GinmanPurchase03/03/20261,515 shares£15.15Gavin GriggsSale16/12/20253,002 shares£27,138.08Gavin GriggsExercise16/12/20256,371 shares£0.00Daniel ShookPurchase24/10/2025768 shares£7,972.45Daniel ShookPurchase22/10/20251,103 shares£11,444.73DateDirector/PDMRTypeSharesPriceValue02/10/2026Matt WebbSale16,3122,022.00£329,910.2002/10/2026Louise WebbPurchase16,3122,022.00£329,910.2002/10/2026Matt WebbSale16,3122,022.00£329,910.2002/10/2026Louise WebbPurchase16,3122,022.00£329,910.2004/03/2026Jamie PikePurchase7,4961.00£74.9603/03/2026Charlotta GinmanPurchase1,5151.00£15.1516/12/2025Gavin GriggsSale3,002904.00£27,138.0816/12/2025Gavin GriggsExercise6,3710.00£0.0024/10/2025Daniel ShookPurchase7681,038.08£7,972.4522/10/2025Daniel ShookPurchase1,1031,037.60£11,444.73
Open positions onlyAberdeen Group plc28/09/20261,413,626 shares5.04%Aberdeen Group plc28/09/20261,413,626 shares5.04%The Wellcome Trust Limited as trustee of The Wellcome Trust07/08/20261,379,123 shares4.92%Ameriprise Financial, Inc.22/05/20261,377,513 shares4.91%JPMorgan Asset Management Holdings Inc.07/05/20261,434,191 shares5.12%Ameriprise Financial, Inc.05/05/20261,434,836 shares5.12%Odyssean Investment Trust PLC30/04/20262,650,000 shares9.45%Ameriprise Financial, Inc.08/12/20251,395,278 shares4.98%Ameriprise Financial, Inc.13/10/20251,443,565 shares5.15%JANUS HENDERSON GROUP PLC24/09/20251,383,854 shares4.94%The Wellcome Trust Limited as trustee of The Wellcome Trust14/08/20251,796,317 shares6.43%Ameriprise Financial, Inc.02/05/20251,377,148 shares4.93%Odyssean Investment Trust PLC24/04/20252,950,000 shares10.56%Aberforth Partners LLP22/04/20252,814,839 shares10.08%DateShareholderShares HeldPercentage28/09/2026Aberdeen Group plc1,413,6265.04%28/09/2026Aberdeen Group plc1,413,6265.04%07/08/2026The Wellcome Trust Limited as trustee of The Wellcome Trust1,379,1234.92%22/05/2026Ameriprise Financial, Inc.1,377,5134.91%07/05/2026JPMorgan Asset Management Holdings Inc.1,434,1915.12%05/05/2026Ameriprise Financial, Inc.1,434,8365.12%30/04/2026Odyssean Investment Trust PLC2,650,0009.45%08/12/2025Ameriprise Financial, Inc.1,395,2784.98%13/10/2025Ameriprise Financial, Inc.1,443,5655.15%24/09/2025JANUS HENDERSON GROUP PLC1,383,8544.94%14/08/2025The Wellcome Trust Limited as trustee of The Wellcome Trust1,796,3176.43%02/05/2025Ameriprise Financial, Inc.1,377,1484.93%24/04/2025Odyssean Investment Trust PLC2,950,00010.56%22/04/2025Aberforth Partners LLP2,814,83910.08%
